New England Patriots vs San Francisco 49ers Prediction and Picks – September 29th, 2024

Home » New England Patriots vs San Francisco 49ers Prediction and Picks – September 29th, 2024

Patriots vs. 49ers – NFL Week 4 Matchup (September 29, 2024)

The New England Patriots (1-2) face off against the San Francisco 49ers (1-2) this Sunday at Levi’s Stadium. The 49ers are heavy favorites in this game, with both teams looking to bounce back after challenging starts to their seasons.

Current Odds:

  • Spread: 49ers -10.5, Patriots +10.5
  • Moneyline: 49ers -588, Patriots +460
  • Over/Under: 42 points

Team Previews:

New England Patriots (1-2):
The Patriots’ offense has struggled this season, managing only 13 points per game, the second-lowest in the league. Veteran quarterback Jacoby Brissett has thrown for just 368 yards and one touchdown across three games, with most of New England’s offensive production coming from their ground game, led by Rhamondre Stevenson and Antonio Gibson. Defensively, the Patriots are allowing 244.3 passing yards per game, ranking 27th in the NFL.

With Brissett under center and the offense facing issues, New England will need to rely on their strong run defense, which has been one of the few bright spots, allowing just 83 rushing yards per game.

San Francisco 49ers (1-2):
San Francisco enters this game as a double-digit favorite, with Brock Purdy leading the offense. Purdy has been effective so far, throwing for 842 yards and four touchdowns with a 72.6% completion rate. Jordan Mason has emerged as the lead back following Christian McCaffrey’s injury, averaging 108 yards per game this season. The 49ers will lean on their balanced attack, featuring Jauan Jennings and Deebo Samuel, to move the ball against New England’s defense.

The 49ers’ defense, led by Nick Bosa and Fred Warner, ranks in the top 10 against the run, and they will look to exploit New England’s offensive woes.

Key Factors:

49ers’ Ground Game: Jordan Mason has been dominant this season, and with New England’s defense showing cracks, he could have another big performance.

Patriots’ Offensive Struggles: With a lackluster passing game and an inconsistent offense, New England will need a near-perfect defensive effort to stay competitive in this game.

Betting Picks:

Against the Spread: The 49ers are favored by 10.5 points. Given their balanced offensive attack and New England’s struggles on offense, 49ers -10.5 seems like the smart play.

Our Pick: San Francisco 49ers -10.5

Over/Under: The total is set at 42 points. With the 49ers likely to control the game and the Patriots struggling to score, the Under 42 points looks like a safe bet.

Our Pick: Under 42

Final Prediction:

    • 49ers 27, Patriots 13

Expect the 49ers to control this game with their run game and strong defense, covering the spread with the total staying under.

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