Jacksonville Jaguars vs Buffalo Bills Prediction and Picks – September 23rd, 2024

Home » Jacksonville Jaguars vs Buffalo Bills Prediction and Picks – September 23rd, 2024

Tonight’s highly anticipated Week 3 matchup between the Jacksonville Jaguars and Buffalo Bills kicks off at 7:30 PM ET at Highmark Stadium in Buffalo. Both teams are looking to make an early-season statement in this Monday Night Football showdown.

Current Odds:

  • Spread: Bills -4.5, Jaguars +4.5
  • Moneyline: Bills -245, Jaguars +205
  • Over/Under: 46.5 points

Team Previews:

Buffalo Bills (2-0):
The Bills have been dominant so far this season, winning their first two games against Arizona and Miami. Buffalo’s defense has been solid, allowing only 19 points per game. Josh Allen has been efficient, passing for 371 yards and three touchdowns without an interception, while James Cook has added a steady running game. Buffalo’s high-scoring offense, which averages 32.5 points per game, will look to continue their momentum at home​.

Jacksonville Jaguars (0-2):
On the other side, the Jaguars have had a tough start to the season, struggling to generate points, with only 15 per game so far. Trevor Lawrence has yet to hit his stride, but Jacksonville’s running game, led by Travis Etienne, has been decent. The Jags’ defense ranks 9th in points allowed, giving them a chance to keep this game competitive. However, they’ll need a much-improved offensive performance to upset the Bills.

Key Factors:

  1. Buffalo’s Offense vs. Jaguars’ Defense:
    Josh Allen will likely test Jacksonville’s secondary, which has struggled to contain passing attacks. With Stefon Diggs and Gabe Davis providing strong receiving options, the Bills will look to exploit Jacksonville’s defense, especially through the air.
  2. Jacksonville’s Ground Game:
    If the Jaguars are to keep this close, they will rely on Travis Etienne to control the clock and move the chains. Buffalo has been vulnerable to the run this season, allowing 131.5 yards per game.

Betting Picks:

  1. Against the Spread:
    While the Bills are favored by 4.5 points, the Jaguars have shown a tendency to keep games close against Buffalo, as they did in a previous matchup last year. Given the trends and Jacksonville’s motivation to avoid a 0-3 start, taking Jaguars +4.5 feels like the safer pick.
  2. Over/Under:
    The total is set at 46.5 points. Jacksonville’s defense has played well enough to limit opponents, while their offense hasn’t scored much. Combining this with Buffalo’s defensive strength, this game is likely to fall under 46.5 points​.

Final Prediction:

  • Bills 24, Jaguars 17
    Buffalo takes the win, but Jacksonville covers the spread, and the total points stay under.
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